The Dons starting eleven contained eight of their under 18s team and three first year professionals with some first team experience, whilst the Rebels also made several changes from their win over Kettering on Saturday. Gavin James started for the first time since 1 October following an injury lay-off, and New Zealand winger Tom Biss made his full debut.
Slough started quickly, with Lewis Putman firing over the bar in the opening minute, and Elijah Adebayo – playing the final match of his loan spell before returning to Fulham – went close after goalkeeper Charlie Burns pushed a dangerous Putman cross in his direction.
But MK Dons grew into the game, playing the ball around nicely on the Arbour Park surface. Right winger Bradley Bell got in a good cross which was headed over, and shortly after another dangerous cross from Bell was eventually cleared.
Slough created more though, and after James curled wide on his left foot, the Rebels took the lead through Adebayo’s 23rd-minute header from Putman’s left wing delivery.
The visitors kept their passing game going and Connor Furlong almost made a chance for Kabongo Tshimanga, but Scott took him wide.
As the first half drew to a close, Burns kept his side in the game with good low stops from James and Mark Nisbet, whilst Scott also made a simple save from Andrew Osei-Bonsu.
Slough started the second half firmly in the ascendancy and twice went close, with James putting a header just wide and Putman seeing a shot cleared off the line.
Furlong almost found himself through on goal for MK Dons, but his touch was too heavy and Scott gathered.
Biss later spurned a clear chance to double the lead as he found himself with just Burns to beat, but the keeper spread himself and blocked.
But a minute later, Burns was finally beaten for a second time as Nisbet’s half-volley from a Putman corner was turned in by Adebayo.
Chances continued to come for the more experienced Slough Town team in front of a fantastic crowd of 636, with Burns again denying Adebayo, and Biss slicing a shot off target after James worked hard to hold the ball up.
Seven minutes from the end, Slough added a third with top scorer James Dobson, another substitute, arriving unmarked at the back post to turn in Putman’s cross – the winger’s third assist of the evening.
Dobson also rattled the crossbar and Scott preserved the Rebels’ clean sheet with a block from Jay Bird’s lobbed effort in the final minute, whilst Sam Nombe also curled a shot wide.
MK Dons Line up
Charlie Burns, Peter Kioso, Juma Omar (Jenson Wright 75), Tommy Hope, David Kasumu, Andrew Osei-Bonsu, Bradley Bell (Jay Bird 46), Connor Furlong, Sam Nombe, Brandon Thomas-Asante, Kabongo Tshimanga. Substitutes not used: Alfie Jones, Jack Hairican-Harvey, Charlie Pattison.