Steve Bateman's side went into the game knowing that a playoff place would elude them regardless of the result following Biggleswade's victory at Guildford on Wednesday evening. Slough lined up with Adam Logie playing as second striker with Eddie Smith in the absence of the suspended pair of Dan Burnell and Ryan O'Toole.
Logie played well, making a nuisance of himself and chasing lost causes, and Slough went closest in the first half with Danny Murphy's free kick being missed by everyone in the penalty area before bouncing over the bar.
Murphy and Chandiram linked up well on the left, and the pass inside found Smith, who shot just wide from 20 yards.
Ollie Burgess saw his acrobatic effort saved low down by the post in a first half of few chances.
Slough always looked likely to score though, and eight minutes into the second half, Jake Parsons showed good footwork to beat his man and cross into the middle, where Smith was on hand to nod in.
Adam Logie had a shot pushed around the post and captain for the day, Adam Martin, also tried his luck from distance, but it bobbled through to Curfews goalkeeper Tony Oval on the dry uneven surface.
Slough doubled their lead with a spectacular strike from Burgess 30 yards out, the former Chertsey midfielder catching a volley sweetly, with the ball dipping over Oval and just under the bar.
Smith went close to a third, but mistimed his header and the ball went just over the angle of post and bar.
Burgess did superbly to set up another half-chance, but his ball across goal was just behind Logie, and the ball stayed out.
But Slough did notch a late third as substitute Dave Deeney dug out a cross from the right, which Smith headed across Oval and into the far corner to make it 33 for the season and 103 league goals in total for Slough.
Smith almost completed his hat-trick, but was denied by Oval late on.
Chertsey Town Lineup
Tony Oval, Daniel Cox (Matt Thornton), Steve Brown, Matt Brunt, Matt Morris, David Johnston, Rob Carr (Ricky Hogsden), Rob Carrick, Mark Knight, John Pomroy (c), John Flood (Arafat Kabuye). Sub not used: Steve Duff.