After a stale first half, the Rebels came to life in the second half and claimed a deserved win – only their second League victory of the year so far.
The first chance of the game would fall to Slough in the fourth minute as debutant Daniel Roberts – making his first appearance for the Rebels having scored 30 goals for Windsor this season - burst into the box, but his effort was deflected.
The Rebels would again have a sight of goal in the eighth minute as a well-worked corner found Mark Nisbet free at the back-post. His volley was hit cleanly but flew just wide of the post.
Slough limited their visitors largely to efforts from distance with the first coming in the 12th minute, however Jack Turner was equal to the attempt.
The best chance of the first half fell to Slough in the 18th minute. After a flurry of chances the ball fell to Matty Lench who chipped the ball over the goalkeeper only to see his effort cleared away on the line.
It was not until the 41st minute that there would be another sight of goal, as Billericay loanee Billy Clifford clipped the ball into the path of Manny Williams, but his effort was easily saved.
At the break the two sides were level with Slough largely controlling proceedings.
The second half started brightly for Slough as Lee Togwell found space on the edge of the box after a defensive header fell his way. He worked the ball onto his left foot and hit a fierce shot which was met with a stunning save onto the post from Hemel goalkeeper Laurie Walker, with Roberts, following up, unable to turn the ball home.
Roberts was in the middle of the action just minutes later as he was played through on goal, but once again his goal-bound effort was blocked.
Chances dried up until the 67th minute when Roberts once again found his way into the Hemel Hempstead box. Running at great pace, his effort was scuffed wide of the mark.
The Rebels continued to mount significant pressure on the Hemel defence, and almost took the lead with twenty minutes remaining as Clifford expertly weaved his way through to a shooting position, only to be denied by Walker.
Slough’s pressure finally paid dividends shortly after. Lee Togwell thrusted his way through the Hemel backline and calmly finished low past Walker to give Slough a deserved lead.
Debutant Francis Amartey, who signed National League forms this week after leaving Birmingham City, had his first attempt blocked after a powerful run into the box.
The final ten minutes saw Slough attempting to run the clock down to ensure all three points were gained. Josh Jackman came to the rescue with seven minutes remaining to stop a Hemel counter attack and keep Slough ahead.
The Rebels were able to see through the remainder of the game to secure their first League win since January.
Report: Sam Collard
Hemel Hempstead Town Line up
Laurie Walker, Jacques Kpohomouh, Joe Howe, Jordan Parker (c), Darren Ward, Frankie Musonda, Kavan Cotter, Kieran Monlouis, Leon Lobjoit, Arel Amu, Arthur Read. Substitutes: Oliver Swain, Jack Snelus, Matteo Mendy, Herschel Sanchez-Watt, George Paulin.