The Rebels travelled with a squad of 19, including five trialists, all of whom gained valauable minutes. Of the players retained from last season, only Matty Lench was unavailable.
The Robins took a single goal lead into the half time break, and added three further goals in the second half, one a penalty kick.
Slough are back in action on Tuesday evening at Windsor.
Slough Town Line up
Jack Turner, Josh Jackman, Trialist A, Sam Togwell, Guy Hollis, Lee Togwell, Max Worsfold, Trialist B, Ben Harris, Trialist C, Warren Harris, Trialist D, Trialist E, Aaron Kuhl, Sean Fraser, Dan Roberts, Ryan Bird, Jack McKnight, Paul Hodges.